SOLACE: The Ultimate Blend to Support Calm, Relaxation, Restful Sleep, and Pain Relief

In today’s fast-paced world, anxiety, sleep disturbances, and chronic pain are common challenges. Whether it's the mental toll of stress or the physical strain of muscle tension and discomfort, finding natural solutions to promote relaxation, alleviate pain, and support restful sleep has never been more important.

That’s where SOLACE comes in. This thoughtfully crafted blend of BIOACTIVE and SUPERFOOD ingredients combines the power of nature with modern science. This article will explore the key ingredients in SOLACE, diving deep into the science behind their effects and how they may contribute to overall well-being by supporting relaxation, improving sleep quality, reducing stress, and promoting pain relief.

BIOACTIVE Ingredients in SOLACE

The BIOACTIVE ingredients in SOLACE are carefully chosen for their ability to address key aspects of mental and physical health. Each ingredient has been scientifically researched for its capacity to relax the body, reduce stress, improve sleep, or support pain relief. When combined, they work synergistically to create an effective formula that promotes holistic health.

1. Magnesium Glycinate

Magnesium Glycinate is a highly bioavailable form of magnesium, a mineral involved in more than 300 biochemical processes in the body. Magnesium plays an essential role in regulating neurotransmitters, promoting muscle relaxation, and supporting the nervous system, making it crucial for both mental calm and physical well-being. Magnesium has also long been recognized for its calming effects. It helps regulate the GABA receptors in the brain, which are responsible for calming neural activity and promoting relaxation.

Research indicates that magnesium supplementation can significantly improve sleep quality, particularly in individuals who struggle with insomnia. A study in the journal The Journal of Research in Medical Sciences found that magnesium supplementation improved sleep efficiency and duration in elderly individuals (Abbasi et al., 2012). Magnesium also plays a crucial role in reducing pain perception. It has been shown to help alleviate muscle tension and reduce the severity of migraines. A study published in Headache showed that magnesium supplementation reduced the frequency of migraines by 41.6% in individuals with low magnesium levels (Chiu et al., 2003). By modulating NMDA receptors involved in pain processing, magnesium can help reduce muscle spasms and discomfort associated with chronic pain (Zeng et al., 2015).

2. Corydalis Extract

Corydalis, a plant used in traditional Chinese medicine, is known for its pain-relieving properties, particularly for its ability to ease both chronic and acute discomfort. The active compound dehydrocorybulbine (DHCB) has been identified as a key contributor to Corydalis' analgesic (pain-relieving) effects. In animal models, it has shown to reduce pain significantly, with effects comparable to opioid medications—but without the addictive potential. A study published in Pain Medicine found that Corydalis extract significantly reduced pain sensitivity in rats with inflammatory pain (Liao et al., 2014). This makes it a valuable ingredient for reducing pain caused by inflammation, muscle spasms, and tension. In addition to its analgesic effects, Corydalis is also known for its calming properties. It promotes relaxation by modulating the nervous system and reducing stress. Studies have shown that Corydalis helps reduce symptoms of anxiety and stress, making it an ideal ingredient for supporting overall mental well-being (Zhang et al., 2010).

3. Chamomile Extract

Chamomile is a well-known herb for promoting relaxation and sleep, and has been studied extensively for its sedative effects. A study published in The Journal of Clinical Psychopharmacology found that chamomile extract improved sleep quality and reduced anxiety in individuals with generalized anxiety disorder (Amsterdam et al., 2009). Its ability to promote relaxation and reduce anxiety makes it an excellent choice for managing stress and promoting a restful night’s sleep. Its active compounds, apigenin and luteolin, interact with GABA receptors in the brain, helping to calm the nervous system and encourage restful sleep. In addition to its calming effects, chamomile also offers pain-relieving properties. Research has shown that chamomile can reduce muscle spasms and ease discomfort, particularly menstrual pain. A study published in BMC Complementary and Alternative Medicine found that chamomile extract significantly reduced the severity of pain in individuals suffering from dysmenorrhea (Sadeghi et al., 2015).

4. Guava Leaf Extract

Guava leaves contain bioactive compounds like quercetin, which is known for its antioxidant and anti-inflammatory effects. Quercetin has been shown to reduce pain and inflammation by inhibiting pro-inflammatory cytokines and suppressing the production of nitric oxide. Research published in Phytomedicine found that guava leaf extract exhibited significant pain-relieving effects, particularly in animal models (Zhang et al., 2015). This makes it a valuable addition for both alleviating pain and promoting relaxation. Studies have also shown that quercetin can have a positive impact on anxiety levels, particularly by reducing oxidative stress in the body (Vidal et al., 2013), thus making guava leaf extract an option for stress relief of the body and mind.

5. Baikal Skullcap Extract 

Baikal Skullcap is an herb traditionally used for its sedative and calming effects. The active compounds wogonin and baicalin are thought to contribute to its ability to reduce stress and promote a sense of calm. Research published in Phytotherapy Research found that the active compounds in Baikal Skullcap had significant anxiolytic (anxiety-reducing) effects, making it an ideal herb for stress relief (Li et al., 2010). Baikal Skullcap also has anti-inflammatory and pain-relieving properties. A study in Phytomedicine found that Baikal Skullcap extract significantly reduced inflammation and pain in animal models (Li et al., 2010), suggesting it may be an effective option for alleviating both mental and physical discomfort.

6. Chrysin

Chrysin is a flavonoid found in passionflower and other plants. Chrysin is well-known for its calming effects, particularly for reducing anxiety and promoting better sleep. Research has shown that Chrysin enhances the activity of GABA, a neurotransmitter that plays a major role in relaxation and stress relief. A study published in Phytotherapy Research showed that Chrysin supplementation helped reduce anxiety and promote a sense of calm in individuals (Liu et al., 2011). Chrysin also has anti-inflammatory properties that contribute to pain relief. A study published in Phytotherapy Research demonstrated that Chrysin reduced the production of pro-inflammatory cytokines and alleviated pain in animal models (Liu et al., 2011). This makes Chrysin a beneficial ingredient for managing both pain and stress.

7. Passionfruit Extract

Passionfruit, known for its sweet, tangy flavor, offers more than just a tasty treat. The extract from the fruit is packed with bioactive compounds that are particularly known for their ability to promote relaxation and improve sleep. The vitexin in passionfruit interacts with GABA receptors in the brain, reducing neuronal excitability and supporting a calming effect, which can lead to improved sleep quality. A study on passionflower extract (a close relative) found that it improved sleep and reduced insomnia symptoms, suggesting similar benefits for passionfruit (Kennedy et al., 2011).

Passionfruit extract also has mild anxiolytic properties, meaning it can help reduce stress and anxiety. The flavonoids, especially vitexin, have been shown to modulate the body's stress response, promoting a sense of calm (Akinmoladun et al., 2014). While passionfruit is primarily known for its relaxation benefits, it may also offer mild pain-relieving effects. The extract contains anti-inflammatory compounds that help reduce pain caused by inflammation. Studies show that flavonoids like vitexin inhibit inflammatory markers, which can help ease discomfort associated with conditions like muscle tension or mild pain (Zhao et al., 2014). Additionally, the potassium in passionfruit aids in muscle relaxation, which may contribute to alleviating cramps or spasms.

8. Passionflower Extract

Passionflower is a well-known herb for its ability to reduce anxiety and improve sleep. The active compound vitexin has been shown to help calm the nervous system and promote relaxation. Passion Flower extract is often used as a natural remedy for anxiety and insomnia. Studies have demonstrated that Passion Flower can significantly reduce anxiety levels and improve sleep quality. A study in The Journal of Clinical Pharmacy and Therapeutics found that Passion Flower extract improved sleep quality and reduced anxiety in individuals with generalized anxiety disorder (Akinmoladun et al., 2014). Passion Flower extract’s ability to relieve pain has been demonstrated in various studies. A study published in The Journal of Pain found that Passion Flower significantly reduced pain perception in both acute and chronic pain conditions (Dimpfel et al., 2009).

9. Kanna Extract (Sceletium tortuosum)

Kanna (Sceletium tortuosum) is a succulent plant native to South Africa, traditionally used for its mood-enhancing, stress-relieving, and cognitive-enhancing properties. Kanna extract is a powerful adaptogen and mood modulator. The active compounds, especially mesembrine, make it effective for promoting relaxation, reducing anxiety, and supporting mental clarity. The cognitive and mood benefits, paired with its potential to assist with pain management through its influence on serotonin and cortisol, make Kanna an important ingredient in SOLACE. Its effects are well-documented in clinical research, supporting its inclusion in this blend designed for relaxation, stress relief, and overall well-being.

The key active compounds found in Kanna include mesembrine, mesembrenone, and mesembrenol, alkaloids that have shown significant pharmacological effects in preclinical and clinical research. These compounds act primarily by inhibiting the serotonin reuptake system and modulating phosphodiesterase 4 (PDE4) activity, resulting in enhanced mood, reduced anxiety, and cognitive support.

Kanna is often used to support mental well-being, particularly in reducing stress and enhancing mood. Research has indicated that mesembrine, the main alkaloid in Kanna, is a potent serotonin reuptake inhibitor (SRI), which means it prevents the reabsorption of serotonin in the brain, leading to higher levels of this "feel-good" neurotransmitter. Increased serotonin levels are commonly associated with improved mood, stress relief, and a reduction in feelings of anxiety. One study published in the Journal of Ethnopharmacology demonstrated that Kanna extract could increase serotonin availability, which may explain its anxiolytic (anxiety-reducing) and antidepressant effects (Gable, 2005).

Further research supports its calming effects on the nervous system. In a clinical trial conducted by Kroboth et al. (2003), it was found that Kanna extract reduced subjective feelings of anxiety in participants under stress, which aligns with its traditional use as a mood stabilizer. The alkaloids found in Kanna are thought to regulate the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol, the body’s primary stress hormone.

Mood, Depression & Anxiety 

Several clinical studies support the efficacy of Kanna in improving mood, reducing anxiety, and enhancing cognitive performance. A study published in the Journal of Ethnopharmacology investigated the effects of Sceletium tortuosum extract in healthy volunteers and reported that the participants who received the extract showed significant improvements in mood and relaxation compared to those who took a placebo (Timmers et al., 2008). Another study from the African Journal of Traditional, Complementary and Alternative Medicines found that Kanna extract could significantly reduce symptoms of anxiety and depression in participants suffering from mood disorders (Wepener et al., 2018). Moreover, Kroboth et al. (2003) conducted a placebo-controlled study on the anxiolytic effects of Kanna extract, confirming that it could reduce the physiological markers of anxiety, including heart rate and cortisol levels.

Pain Relief

In addition to its mood-enhancing and stress-relieving properties, Kanna has also shown potential in reducing pain perception. While research in this area is still emerging, the alkaloids in Kanna appear to influence endorphin levels, which play a crucial role in pain management and emotional regulation. A study in the European Journal of Pain showed that enhancing serotonin levels in the brain and reducing cortisol could have a beneficial effect on chronic pain management (Tontodonati et al., 2007). Kanna's ability to promote relaxation and reduce stress may also indirectly reduce muscle tension, which often contributes to pain and discomfort.

SUPERFOOD Ingredients in SOLACE

Incorporating nutrient-rich SUPERFOODS, SOLACE offers a unique combination of ingredients designed to support relaxation, reduce stress, and promote overall well-being. Each SUPERFOOD ingredient contributes essential vitamins, antioxidants, and bioactive compounds that enhance the blend's effectiveness and create a holistic approach to relaxation and recovery.

1. Mango Fruit Powder

Mango fruit powder brings a tropical richness to the blend while delivering a substantial dose of antioxidants, vitamins, and minerals, including vitamin C, vitamin A, and folate. These nutrients are critical for immune function, skin health, and cellular repair. However, mango's real strength lies in its high levels of polyphenols, particularly mangiferin. Mangiferin is a powerful antioxidant that has been shown to have neuroprotective, anti-inflammatory, and antidiabetic effects. In a study published in Biochimica et Biophysica Acta (2012), researchers highlighted the potential of mangiferin in reducing oxidative stress and modulating inflammatory pathways, which makes it a valuable addition to a relaxation-based supplement like SOLACE (Basu et al., 2012). In addition to its anti-inflammatory properties, mangiferin has been shown to support cognitive function by protecting neurons from oxidative damage, contributing to an overall sense of well-being and reducing the effects of stress on the body (Basu et al., 2019).

2. African Mango Extract

African mango extract, derived from the seeds of Irvingia gabonensis, is increasingly popular for its metabolic benefits, particularly its impact on weight management and appetite control. African mango is rich in soluble fiber, which supports digestion and helps maintain healthy blood sugar levels, aiding insulin sensitivity and influencing inflammatory markers (Ngondi et al., 2009). This extract also supports the body's natural fat metabolism and can help improve blood lipid profiles, offering additional cardiovascular benefits. In a study published in Lipids in Health and Disease (2009), participants who took African mango extract showed significant improvements in body fat percentage, waist circumference, and cholesterol levels compared to those who did not take the supplement (Ngondi et al., 2009). Beyond its metabolic advantages, African mango extract provides satiety, helping users manage their hunger and food cravings, which can be especially beneficial in reducing stress-related eating. In terms of stress and relaxation, the soluble fiber and antioxidant properties of African mango may also help the body cope with oxidative stress, enhancing overall mood and reducing the feelings of fatigue and irritability that often accompany high-stress levels.

3. Tart Cherry Extract

Tart cherry extract, sourced from Prunus cerasus, is widely recognized for its rich anthocyanin and melatonin content. These compounds contribute significantly to its antioxidant properties, offering both mental and physical benefits. Anthocyanins in tart cherries have demonstrated powerful anti-inflammatory effects that can reduce muscle soreness, support recovery post-exercise, and promote overall joint health (Bell et al., 2014). Additionally, the naturally occurring melatonin in tart cherries has been studied for its role in sleep enhancement, shown to improve sleep quality and duration, especially in individuals with insomnia (Pigeon et al., 2010). A study conducted in the European Journal of Nutrition (2013) found that tart cherry juice increased sleep duration by 90 minutes in participants with insomnia, confirming its ability to help promote better sleep quality (Pigeon et al., 2013).

4. Acerola Cherry Extract

Acerola cherry extract, derived from the Malpighia emarginata plant, is celebrated for its high vitamin C content, far surpassing the levels found in most other fruits. Acerola’s vitamin C supports immune function by aiding white blood cell activity, enhancing collagen synthesis, and protecting cells from oxidative damage. Vitamin C also plays a role in reducing the impact of stress on the body, as it helps regulate cortisol levels, which tend to increase under stress (DeRosa et al., 2015). In addition to its immune-boosting properties, acerola cherry extract contains bioflavonoids and carotenoids, compounds that amplify its antioxidant activity. These nutrients provide further cardiovascular protection and support healthy skin. Research in the Journal of Agricultural and Food Chemistry (2013) highlighted the antioxidant potential of acerola cherries, noting that these compounds can significantly reduce oxidative damage, which may improve long-term resilience against physical and mental stress (Assunção et al., 2017).

5. Wild Cherry Extract

Wild cherry extract, taken from the Prunus serotina tree, has a long history of use for respiratory support and its calming properties. Rich in antioxidants such as quercetin and kaempferol, wild cherry is known for its anti-inflammatory and soothing effects. Traditionally, it has been used to treat coughs and other respiratory issues, but its broader benefits include promoting relaxation and reducing stress. Studies published in Phytomedicine (2003) support wild cherry's anti-inflammatory effects. Quercetin, one of the primary flavonoids in wild cherry, has been shown to have potent anti-inflammatory and antioxidant properties, which help reduce systemic inflammation (Giampieri et al., 2012). Beyond its anti-inflammatory benefits, wild cherry may also support relaxation by reducing the physical symptoms of stress, such as muscle tension.

6. Lime Fruit Powder

Lime fruit powder, derived from freeze-dried limes, provides SOLACE with both a bright flavor and a range of health benefits. Limes are rich in vitamin C, flavonoids, and limonoids, which are natural compounds found in citrus fruits. The vitamin C in lime promotes immune health and supports collagen synthesis, essential for skin health and wound healing. Limonoids have shown promise in research for their anti-inflammatory and anticancer potential, further enhancing lime’s health-boosting profile (Manners et al., 2003). Research published in Phytochemistry (2004) has demonstrated that limonoids extracted from citrus fruits, including lime, have antioxidant and anti-inflammatory effects that help reduce oxidative stress and inflammation, common contributors to chronic stress. Additionally, limonoids may help protect against certain types of cancer, underscoring the fruit’s therapeutic potential.

Conclusion: A Holistic Approach to Pain, Stress, and Sleep with SOLACE

By combining these carefully selected BIOACTIVE and SUPERFOOD ingredients, SOLACE offers a comprehensive formula that supports both the body and mind. Whether you’re seeking to alleviate pain, reduce stress, or improve your sleep quality, SOLACE provides natural, scientifically supported ingredients in an easy-to-consume solution. Each ingredient is chosen for its unique ability to promote relaxation, ease discomfort, and support overall well-being, making SOLACE a trusted choice for anyone looking to live life with greater ease and comfort.