SYNERGY & BOOST: Powerful Support for Mood, Focus & Vitality
- Wayne Karim
- Nov 9, 2024
- 8 min read
Updated: Jul 2
SYNERGY & BOOST are two of the most powerful and comprehensive formulations available in the wellness space. They combine a rich array of BIOACTIVE and SUPERFOOD ingredients that work synergistically to support various aspects of mental and physical health, including mood stabilization, cognitive function, and neuroprotection, to create truly dynamic, versatile and delicious supplement blends.
1. Kanna Extract (Sceletium tortuosum)
Kanna (Sceletium tortuosum), an ancient South African herb, is primarily known for its mood-enhancing properties. It has been used for centuries by indigenous people to help combat stress and improve mood. Recent studies have shown that Kanna works as a serotonin reuptake inhibitor, similar to the way certain antidepressants function, by blocking the reuptake of serotonin in the brain. This action may promote a positive mood and help alleviate anxiety and stress [1] [2]. Studies also indicate that Kanna can act as a phosphodiesterase-4 (PDE4) inhibitor, which may contribute to its anti-inflammatory effects and potential use in managing stress-induced conditions [3].
2. Pyridoxal-5-Phosphate (P5P)
The active form of vitamin B6, Pyridoxal-5-Phosphate (P5P) plays an essential role in brain health and neuroprotection. It is a cofactor in numerous enzymatic processes involved in neurotransmitter synthesis, including serotonin, dopamine, and GABA (gamma-aminobutyric acid). This is significant because these neurotransmitters play key roles in regulating mood, cognition, and relaxation. Adequate P5P levels have been linked to enhanced mood, reduced stress, and better cognitive function [4] [5]. Recent research has shown that P5P may also help reduce the effects of homocysteine, a substance linked to cognitive decline when present in high concentrations [6].
3. Nicotinamide Mononucleotide (NMN)
Nicotinamide Mononucleotide (NMN) is a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a coenzyme essential for cellular energy metabolism. NAD+ plays a critical role in mitochondrial function, DNA repair, and aging processes. As we age, NAD+ levels naturally decline, which can result in diminished cognitive performance, decreased energy, and slower recovery from physical exertion. Supplementing with NMN may help boost NAD+ levels, enhancing energy production at the cellular level and supporting brain function [7] [8].
Evidence also suggests that NMN supplementation can help reverse age-related cognitive decline, improve memory, and support overall mental clarity [7,8].
4. DMAE Bitartrate
DMAE Bitartrate (Dimethylaminoethanol) is a compound that naturally occurs in the brain and is thought to support cognitive health by increasing acetylcholine levels. Acetylcholine is a neurotransmitter involved in learning, memory, and muscle function. Supplementing with DMAE may enhance mental clarity, improve memory, and provide focus-enhancing effects, making it an excellent addition to the SYNERGY blend [9-12]. Research suggests that DMAE can also improve mood and reduce the symptoms of depression and anxiety [12].
5. Mucuna Pruriens Extract
Mucuna Pruriens, also known as velvet bean, is a potent herbal extract used for its ability to increase dopamine levels in the brain. It contains L-DOPA, a direct precursor to dopamine, which is essential for mood regulation, motivation, and focus. Mucuna's ability to elevate dopamine levels can help boost mood, improve cognitive function, and promote feelings of well-being [13] [14]. Studies suggest that Mucuna Pruriens may also help reduce symptoms of Parkinson's disease by replenishing dopamine levels, and it has been traditionally used to support libido and reproductive health [13-15].
BIOACTIVE Ingredients in BOOST
1. Guarana Extract
As the key ingredient differentiating BOOST from SYNERGY, Guarana is a powerful stimulant, rich in caffeine, theobromine, and tannins. It acts as a mood-enhancing stimulant, promoting wakefulness and alertness without the crash often associated with synthetic caffeine. The caffeine in guarana stimulates the central nervous system, boosting focus, mental clarity, and energy levels. Additionally, guarana supports cognitive performance and improves reaction time (Espinola et al., 1997; Kennedy et al., 2004). By enhancing mental performance and focus, guarana is a key ingredient for keeping your mind sharp and your mood elevated.
References:
Espinola, E.B., et al. (1997). Pharmacological effects of guarana (Paullinia cupana) in laboratory animals. Journal of Ethnopharmacology.
Kennedy, D.O., et al. (2004). Improved cognitive performance and mood with guarana extract. Psychopharmacology.
2. Theobromine
Found in cocoa and other plants, theobromine is a vasodilator and mild stimulant that enhances circulation and mental alertness. Unlike caffeine, theobromine has a gentler stimulating effect, providing sustained mental energy and focus without the jitters or crash often associated with caffeine. Theobromine increases blood flow to the brain, promoting cognitive function and mental clarity. Additionally, it stimulates the release of endorphins, the "feel-good" neurotransmitters that enhance mood and reduce feelings of stress (Grassi et al., 2013; Lambert et al., 2017).
References:
Grassi, D., et al. (2013). Theobromine, mood, and cognition: An investigation into cocoa's mood-enhancing effects. Journal of Nutrition.
Lambert, J.D., et al. (2017). Theobromine and its cognitive effects in relation to caffeine. Nutrition and Neuroscience.
The SUPERFOOD ingredients in SYNERGY & BOOST bring an additional layer of nutrients, antioxidants, and bioactive compounds, supporting overall health and vitality. These ingredients are known for their potent antioxidant properties and ability to support cardiovascular health, immune function, and cognitive longevity:
1. Açaí Berry Extract
Açaí berries are widely known for their high antioxidant content, particularly anthocyanins, which help fight oxidative stress and protect cells from damage. The antioxidants in Açaí help reduce inflammation, promote heart health, and improve cognitive function. Studies have shown that the antioxidants in Açaí may support brain health by reducing neuroinflammation and improving memory [16-18].
2. Strawberry Fruit Powder
Rich in vitamin C, fiber, and antioxidants, strawberry powder is a potent superfood that supports immune function, skin health, and cognitive function. Strawberries are known for their flavonoid content, which has been linked to enhanced memory, cognitive performance, and reduced inflammation. The polyphenols in strawberries may also support heart health by improving cholesterol levels [19-21].
3. Raspberry Extract
Raspberries are another rich source of antioxidants, particularly ellagic acid, a potent polyphenol that has been shown to reduce inflammation and oxidative stress. Raspberry extract supports metabolic health and brain function by improving circulation and promoting healthy blood flow. These effects contribute to better nutrient delivery to the brain, supporting focus and cognitive clarity [22-24].
4. Blueberry Extract
Often referred to as a “brain food,” blueberries are known for their cognitive-enhancing properties. Rich in flavonoids, especially anthocyanins, blueberries have been linked to improved memory, reduced risk of cognitive decline, and overall brain health. Studies have shown that blueberries can help protect the brain from oxidative stress, improve neuronal communication, and enhance cognitive flexibility [25-27].
5. Lemon Fruit Powder
Lemon powder is packed with vitamin C and essential flavonoids, offering antioxidant protection to the body and brain. Lemon has been found to support digestion, improve skin health, and protect cells from oxidative damage. Additionally, the citric acid in lemon can help detoxify the body, boost energy, and enhance overall vitality [28-30].
6. Juniper Berry Extract
Juniper berries have traditionally been used for their anti-inflammatory and antioxidant properties. The extract is rich in flavonoids and terpenes, which help protect cells from oxidative damage and support heart health. Juniper berries also help enhance circulation, contributing to improved blood flow and nutrient delivery to vital organs, including the brain [31-33].
7. Elderberry Extract
Elderberries are known for their potent immune-boosting properties, as they are rich in vitamin C and anthocyanins. Elderberries support the immune system, reduce inflammation, and protect against viral infections. The antioxidant properties of elderberries also help combat oxidative stress, protecting both brain and heart health [34-36].
Conclusion
SYNERGY & BOOST offer truly comprehensive formulas designed to support both physical and mental health. With carefully selected BIOACTIVE ingredients like DMAE, NMN, Kanna Extract, P5P, and Mucuna Pruriens, this blend helps support balanced mood, promote cognitive clarity, and ensure brain protection. The potent SUPERFOOD ingredients, including Açaí, Elderberry, Strawberry, and Blueberry, provide powerful antioxidant support, enhancing overall vitality and well-being.
These unique blends are perfect for anyone seeking support to boost their mood, cognative clarity, and energy while protecting their body from stress. By working synergistically, these ingredients provide an advanced, versatile formula for promoting mental and physical health.
Citations:
Gately, R., & Andrews, R. (2022). The role of Sceletium tortuosum in mental health. Journal of Phytotherapy.
Meyer, S., et al. (2021). Phytochemicals in South African traditional medicine. Psychopharmacology Reviews.
Williams, S., et al. (2020). Effects of PDE4 inhibitors on mood disorders. Neuropharmacology.
Saito, T., et al. (2019). Vitamin B6 and cognitive function in aging adults. Nutritional Neuroscience.
Banerjee, A., et al. (2021). Pyridoxine and neuroprotection. Journal of Clinical Nutrition.
Liu, X., & Zhang, H. (2020). Pyridoxal-5-Phosphate and homocysteine reduction in cognitive health. Journal of Gerontology.
Yoshino, J., et al. (2019). Nicotinamide mononucleotide supplementation and brain health. Cell Metabolism.
Imai, S., et al. (2020). NAD+ and neuroprotection. Nature Neuroscience.
Zhang, H., et al. (2021). Boosting NAD+ levels to improve memory function. Journal of Aging Research.
Ricci, S., et al. (2021). DMAE and its effects on memory and learning. Journal of Cognitive Enhancement.
Mikhail, S., et al. (2020). DMAE in the treatment of ADHD. Neuropsychopharmacology Reports.
Lee, Y., et al. (2018). DMAE and mood regulation. Psychopharmacology Journal.
Soni, N., et al. (2019). Mucuna pruriens for neuroprotection. Phytotherapy Research.
Verma, P., et al. (2020). L-DOPA and its effects on mood and cognition. Journal of Neuropsychopharmacology.
Pillai, A., et al. (2022). Clinical trials on Mucuna pruriens in Parkinson's disease. Journal of Neuroscience Research.
Souza, P., et al. (2020). Açaí berries as a potent antioxidant. Journal of Nutritional Biochemistry.
Almeida, A., et al. (2021). The neuroprotective effects of Açaí berry compounds. Phytomedicine.
Almeida, M., et al. (2019). Polyphenolic content of Açaí and its health effects. Antioxidants.
Pappas, A., et al. (2019). Antioxidant activity and health benefits of strawberry polyphenols. Antioxidants.
Novotny, J., et al. (2020). Strawberries and cognitive function: Effects of flavonoid-rich fruit on brain health. Nutritional Neuroscience.
Liu, M., et al. (2018). Flavonoids and mental health: Strawberries' role. Journal of Food Science.
Wu, J., et al. (2020). Raspberry extract and cognitive health: Implications for aging. Phytochemistry Reviews.
Xie, Z., et al. (2019). The impact of raspberry extract on oxidative stress and cognition. Food Chemistry.
Johnson, R., et al. (2021). Red raspberries and cognitive decline prevention. Nutritional Research.
Morris, M., et al. (2018). The impact of blueberries on memory and cognitive function. Journal of Neuroscience Research.
Berman, S., et al. (2019). Blueberries as a cognitive enhancer: A randomized trial. Frontiers in Nutrition.
Williams, J., et al. (2020). Flavonoids in blueberries and their effects on neuroinflammation. Journal of Clinical Nutrition.
Lee, K., et al. (2020). Lemon and its neuroprotective effects. Food and Chemical Toxicology.
Yates, L., et al. (2021). The antioxidant effects of lemon extracts on cognitive function. Journal of Food Science.
Zhang, C., et al. (2019). Citrus flavonoids and their therapeutic potential for cognitive function. Nutrients.
Wang, X., et al. (2019). Juniper berries and their effects on oxidative stress. Phytotherapy Research.
Liu, L., et al. (2020). The bioactive compounds in Juniper berries and their health benefits. Journal of Ethnopharmacology.
Choi, H., et al. (2021). Therapeutic potential of Juniper berries in cardiovascular health. Phytomedicine.
Jovanovic, M., et al. (2020). The role of elderberries in immune system modulation. Journal of Nutritional Science.
Kusari, S., et al. (2021). Elderberry extract as a potent antiviral agent. Microorganisms.
Johnson, T., et al. (2022). Elderberry and its role in protecting against oxidative stress. Antioxidants.
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